List of largest selling pharmaceutical products

From Wikipedia, the free encyclopedia

Boehringer Ingelheimclick here for best products of diabetes

This article's factual accuracy is disputed. Please help to ensure that disputed statements are reliably sourced. See the relevant discussion on the talk page. (October 2015)

This article's factual accuracy is disputed. Please help to ensure that disputed statements are reliably sourced. See the relevant discussion on the talk page. (November 2015)

The following is a list of the top 100 pharmaceutical products ranked by sales in U.S. dollars for April 2014 through March 2015.

Rank	Brand Name(s)	Generic Name	Sales 2014-15Sales ($000)	Change from 2013-14	Company(ies)	Disease/Medical Use	First Approval Date	Patent Expiration Date[1][2]
1	Synthroid	Levothyroxine	21,561,481	-2.50%	Abbott Laboratories	Hypothyroidism	May-1999	Mon-20XX
2	Crestor	Rosuvastatin	21,478,776	4.53%	AstraZeneca, Shionogi	Cholesterol	Nov-2002	Jul-2016
3	Ventolin HFA	Salbutamol	18,203,939	0.00%	GlaxoSmithKline	Asthma; chronic obstructive pulmonary disease	May-1981	Mon-20XX
4	Nexium	Esomeprazole	15,298,228	0.74%	AstraZeneca	Gastrointestinal disorders	Mar-2000	May-2014
5	Advair Diskus, Seretide	Fluticasone/salmeterol	13,776,325	2.65%	GlaxoSmithKline	Asthma	Aug-2000	Mar-2012
6	Lantus Solostar	Insulin glargine	10,939,840	9.39%	Sanofi-Aventis	Diabetes mellitus type 1 and 2	Apr-2000	Dec-2011
7	Vyvanse	Lisdexamfetamine	10,413,999	9.39%	Shire	Attention deficit hyperactivity disorder	Dec-1990	Mon-20XX
8	Lyrica	Pregabalin	10,022,365	2.82%	Pfizer	Neuropathic pain	Jul-2004	Jul-2019
9	Spiriva Handihaler	Tiotropium bromide	9,635,935	3.39%	Boehringer Ingelheim	Chronic obstructive pulmonary disease	Apr-2002	Jul-2018
10	Januvia	Sitagliptin	9,148,946	3.63%	Merck & Co., Inc.	Diabetes mellitus type 2	Dec-1996	Nov-2017
11	Lantus	Insulin glargine	9,145,153	5.84%	Sanofi-Aventis	Diabetes mellitus type 1 and 2	Apr-2000	Dec-2011
12	Abilify	Aripiprazole	9,099,978	2.23%	Bristol-Myers Squibb,Otsuka Pharmaceutical	Psychosis; depression	Nov-2002	Oct-2014
13	Symbicort	Budesonide/formoterol	8,265,594	9.63%	AstraZeneca	Asthma	Aug-2000	Mon-20XX
14	Tamiflu	Oseltamivir	8,025,275	0.00%	Chugai Pharmaceutical,Hetero Drugs, Roche	Influenza	Oct-1999	Mon-20XX
15	Cialis	Tadalafil	7,472,719	4.58%	Eli Lilly and Company,Lilly Icos	Erectile dysfunction	Nov-2002	Mon-20XX
16	Viagra	Sildenafil	7,104,074	3.26%	Pfizer	Erectile dysfunction	Mar-1998	Mar-2012
17	Suboxone	Buprenorphine	6,985,631	-2.11%	Reckitt Benckiser Pharmaceuticals Inc.	Pain; opioid addiction	Aug-2000	Mon-20XX
18	Zetia	Ezetimibe	6,925,137	4.04%	Merck & Co., Schering-Plough	Cholesterol	Oct-2002	Oct-2017
19	Xarelto	Rivaroxaban	6,739,752	18.72%	Bayer	Oral anticoagulant	Dec-1996	Sep-2012
20	Bystolic	Nebivolol	6,461,435	10.72%	Forest Laboratories, Inc	Hypertension	Dec-1996	Sep-2012
21	Celebrex	Celecoxib	6,449,730	5.23%	Pfizer	Osteoarthritis; rheumatoid arthritis	Dec-1998	May-2014
22	Nasonex	Mometasone	6,432,382	5.67%	Schering-Plough	Allergic rhinitis	Oct-1997	Oct-2018
23	Namenda	Memantine	5,961,360	-6.00%	Forest Laboratories	Alzheimer's disease	Oct-2003	Apr-2015
24	Flovent HFA	Fluticasone propionate	5,736,650	13.97%	GlaxoSmithKline	Asthma	Mar-1996	Mon-20XX
25	OxyContin	Oxycodone	5,347,532	2.91%	Purdue Pharma	Pain	Dec-1996	Mon-20XX
26	Diovan	Valsartan	5,224,025	-2.80%	Novartis	Hypertension	Dec-1996	Sep-2012
27	Thyroid	Valsartan	5,128,576	20.80%	Novartis	Hypertension	Dec-1996	Sep-2012
28	Voltaren Gel	Diclafenac sodium	5,123,676	18.80%	Novartis	Hypertension	Dec-1996	Sep-2012
29	Nuvaring	Valsartan	4,917,514	18.80%	Novartis	Hypertension	Dec-1996	Sep-2012
30	Afluria	Valsartan	4,650,167	18.80%	Novartis	Hypertension	Dec-1996	Sep-2012
31	Dexilant	Dexlansoprazole	4,620,902	17.57%	Takeda Pharmaceuticals North America, Inc	Gastrointestinal disorders	Dec-2004	Jul-2012
32	Benicar	Olmesartan/hydrochlorothiazide	4,483,555	13.22%	Daiichi Sankyo	Hypertension	Jun-1909	Apr-2016
33	Proventil HFA	Olmesartan/hydrochlorothiazide	4,385,623	13.22%	Daiichi Sankyo	Hypertension	Jun-1909	Mon-2016
34	Humalog	Insulin lispro	4,209,193	6.15%	Eli Lilly and Company	Diabetes mellitus type 1 and 2	Apr-1996	Mon-20XX
35	NovoLog FlexPen	Insulin aspart	4,179,914	7.84%	Novo Nordisk	Diabetes mellitus type 1 and 2	Oct-1996	Mon-20XX
36	NovoLog	Insulin aspart	3,968,615	3.86%	Novo Nordisk	Diabetes mellitus type 1 and 2	Oct-1996	Mon-20XX
37	Vesicare	Solifenacin	3,686,182	15.37%	Astellas Pharma US	Overactive bladder	Feb-2000	Nov-2018
38	Premarin	Solifenacin	3,462,987	15.37%	Astellas Pharma US	Overactive bladder	Feb-2000	Nov-2018
39	Benicar HCT	Olmesartan/hydrochlorothiazide	3,352,383	13.22%	Daiichi Sankyo	Hypertension	Jun-1909	Mon-2016
40	Lo Loestrin Fe	Olmesartan/hydrochlorothiazide	3,335,659	13.22%	Daiichi Sankyo	Hypertension	Jun-1909	Mon-2016
41	Lumigan	Olmesartan/hydrochlorothiazide	3,298,208	13.22%	Daiichi Sankyo	Hypertension	Jun-1909	Mon-2016
42	Namenda XR	Memantine	3,157,234	-6.00%	Forest Laboratories	Alzheimer's disease	Oct-2003	Apr-2015
43	Humalog KwikPen	Insulin lispro	3,043,015	19.02%	Eli Lilly and Company	Diabetes mellitus type 1 and 2	Apr-1996	Mon-20XX
44	Janumet	Sitagliptin/metformin	3,027,293	4.65%	Merck & Co., Inc.	Diabetes mellitus type 2	Dec-1998	Mon-20XX
45	Pataday	Sitagliptin/metformin	2,905,818	4.65%	Merck & Co., Inc.	Diabetes mellitus type 2	Dec-1998	Mon-20XX
46	Ortho-Tri-Cy Lo 28	Sitagliptin/metformin	2,900,301	4.65%	Merck & Co., Inc.	Diabetes mellitus type 2	Dec-1998	Mon-20XX
47	Travatan Z	Sitagliptin/metformin	2,861,717	4.65%	Merck & Co., Inc.	Diabetes mellitus type 2	Dec-1998	Mon-20XX
48	CombiventRespimat	Atorvastatin	2,846,891	14.23%	Generic	Cholesterol	Dec-1996	Nov-2011
49	Toprol-XL	Atorvastatin	2,811,156	14.23%	Generic	Cholesterol	Dec-1996	Nov-2011
50	Pristiq	Atorvastatin	2,769,837	14.23%	Generic	Cholesterol	Dec-1996	Nov-2011
51	Invokana	Atorvastatin	2,711,901	14.23%	Generic	Cholesterol	Dec-1996	Nov-2011
52	Minastrin 24 Fe	Atorvastatin	2,555,803	14.23%	Generic	Cholesterol	Dec-1996	Nov-2011
53	Strattera	Atomoxetine	2,418,649	14.23%	Eli Lilly and Company	attention deficit hyperactivity disorder	Dec-1996	Nov-2016
54	Seroquel XR	Quetiapine	2,390,205	-2.22%	AstraZeneca	Psychosis; depression	Sep-1997	Mar-2012
55	Vytorin	Ezetimibe/simvastatin	2,384,517	13.02%	Merck & Co., Schering-Plough	Cholesterol	Jul-2004	Mon-20XX
56	Focalin XR	Ezetimibe/simvastatin	2,334,004	13.02%	Merck & Co., Schering-Plough	Cholesterol	Jul-2004	Mon-20XX
57	Dulera	Ezetimibe/simvastatin	2,307,692	13.02%	Merck & Co., Schering-Plough	Cholesterol	Jul-2004	Mon-20XX
58	Levemir Flexpen	Insulin detemir	2,283,328	-9.34%	Novo Nordisk	Diabetes mellitus type 1 and 2	Dec-1990	Mon-20XX
59	Zostavax	Zostavax	2,279,662	15.17%	Eisai, Merck & Co.	Herpes zoster	Aug-1999	May-2013
60	Avodart	Dutasteride	2,271,799	15.17%	GlaxoSmithKline	benign prostatic hyperplasia	Aug-1999	Nov-2015
61	Pradaxa	Dabigatran	2,257,507	10.53%	Boehringer Ingelheim,Lilly Icos	Oral anticoagulant	Oct-2010	Mon-20XX
62	Chantix	Dabigatran	2,208,377	10.53%	Boehringer Ingelheim,Lilly Icos	Oral anticoagulant	Oct-2010	Mon-20XX
63	Eliquis	Dabigatran	2,179,340	10.53%	Boehringer Ingelheim,Lilly Icos	Oral anticoagulant	Oct-2010	Mon-20XX
64	Humira	Adalimumab	2,173,082	3.86%	AbbVie	Crohn's disease; Rheumatoid arthritis	Dec-2002	Dec-2016
65	Levemir Flextouch	Insulin detemir	2,164,191	-9.34%	Novo Nordisk	Diabetes mellitus type 1 and 2	Dec-1990	Mon-20XX
66	Levemir	Insulin detemir	2,100,856	-9.34%	Novo Nordisk	Diabetes mellitus type 1 and 2	Dec-1990	Mon-20XX
67	Victoza 3-Pak	Liraglutide	2,078,630	-9.59%	Novo Nordisk	Diabetes mellitus type 2	May-1909	Mon-20XX
68	Combigan	Brimonidine and Timolol	1,909,750	-9.59%		Open angle Glaucoma	May-1909	Mon-20XX
69	Exelon		1,825,705	9.59%		Diabetes mellitus type 2	May-1909	Mon-20XX
70	Tradjenta	Linagliptin	1,744,708	9.59%	Boehringer Ingelheim, Lilly Icos	Diabetes mellitus type 2	May-1909	Mon-20XX
71	Premarin Vaginal		1,738,728	9.59%		Diabetes mellitus type 2	May-1909	Mon-20XX
72	Enbrel	Etanercept	1,691,819	1.46%	Amgen	Rheumatoid arthritis	Nov-1998	Oct-2012
73	Onglyza	Etanercept	1,691,615	1.46%	Amgen	Rheumatoid arthritis	Nov-1998	Oct-2012
74	Ranexa	Etanercept	1,661,050	1.46%	Amgen	Rheumatoid arthritis	Nov-1998	Oct-2012
75	Truvada	Tenofovir/emtricitabine	1,651,083	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
76	Welchol	Tenofovir/emtricitabine	1,644,996	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
77	Linzess	Tenofovir/emtricitabine	1,639,652	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
78	Latuda	Tenofovir/emtricitabine	1,635,230	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
79	Alphagan P	Tenofovir/emtricitabine	1,483,322	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
80	Viibryd	Tenofovir/emtricitabine	1,425,156	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
81	Effient	Prasugrel	1,406,934	0.03%	Gilead Sciences	Prevent blood clots	Apr-2004	Mon-2017
82	Norvir	Tenofovir/emtricitabine	1,376,523	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
83	Amitiza	Tenofovir/emtricitabine	1,371,937	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
84	Azor	Tenofovir/emtricitabine	1,338,802	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
85	Advair HFA	Tenofovir/emtricitabine	1,310,993	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
86	Uloric	Tenofovir/emtricitabine	1,293,249	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
87	Lotemax	Tenofovir/emtricitabine	1,245,330	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
88	Myrbetriq	Tenofovir/emtricitabine	1,230,040	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
89	Asmanex Twisthaler	Tenofovir/emtricitabine	1,219,923	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
90	Epiduo	Tenofovir/emtricitabine	1,212,887	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
91	Xopenex HFA	Tenofovir/emtricitabine	1,204,025	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
92	Durezol	Tenofovir/emtricitabine	1,189,206	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
93	Patanol	Tenofovir/emtricitabine	1,181,134	0.03%	Gilead Sciences	HIV infecticlick here for product of diabeteson	Aug-2004	Mon-20XX
94	Atripla	Emtricitabine/tenofovir/efavirenz	1,147,295	-10.36%	Gilead Sciences, Inc.	HIV infection	Dec-1996	Mar-2015
95	Aggrenox	Tenofovir/emtricitabine	1,144,739	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
96	Exforge	Tenofovir/emtricitabine	1,134,532	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
97	Humulin R	Tenofovir/emtricitabine	1,110,123	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
98	Carafate	Tenofovir/emtricitabine	1,110,008	0.03%	Gilead Sciences	HIV infection	Aug-2004	Mon-20XX
99	Novolog Flxpen Mix 70/30	Insulin aspart	1,069,219	3.86%	Novo Nordisk	Diabetes mellitus type 1 and 2	Oct-1996	Mon-20XX
100	Relpax	Eletriptan	1,035,265	0.03%	Pfizer Inc	migraine headaches	Aug-2004	Dec-2016